Worried about high blood pressure?

Join the High Blood Pressure Clinical Study.

The study is for people who have been diagnosed with high blood pressure. The clinical study examines whether an investigational procedure may help reduce blood pressure without adding more medications.


Take a short survey to see if this study may be right for you.

See if you qualify

Get the facts abouthigh blood pressure.

Did you know that more than 50% of adults in the United States live with high blood pressure?

Even though high blood pressure is very common, it can be hard to treat. In fact, four out of five people with high blood pressure don't have it under control.¹

High blood pressure can cause serious issues, even if you don't have symptoms.

Your heart has to work harder if you have high blood pressure, which can raise your risk of heart attacks, strokes, heart failure, and kidney failure.²⁻³  These risks can be very serious—especially if your high blood pressure is left untreated.

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High blood pressure raises your risk of:

Heart failure²

Heart attack²

Stroke²

Kidney disease³

When should you treat it?

Normal<120 / <80
Elevated120-129 / <80
Stage 1130-139 / 80-89
normal treatment point
Stage  2≥140 / ≥90
Hypertensive Crisis≥180 / ≥120

How high is too high?

The American Heart Association and the American College of Cardiology recommend treating high blood pressure at: 

130/80 mmHg⁴

Your need for treatment depends on your individual situation, including your overall health, family history, and other risk factors.


Diet, exercise, and other lifestyle changes can also help you achieve your blood pressure goals.

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What is the High Blood Pressure Clinical Study?

This clinical study investigates whether a new treatment may help reduce high blood pressure without additional medications.‍


The clinical study may be a good fit for you if you are:


  • Interested in an investigational procedure that may help reduce high blood pressure without adding more medications.
  • Want to learn more about an option that may reduce health risks associated with uncontrolled high blood pressure.
  • Want to help advance science for people diagnosed with high blood pressure.


See if you qualify

How does it work?

The High Blood Pressure Clinical Study evaluates the safety, effectiveness, and long-term impact of the Medtronic Symplicity™ blood pressure procedure.‍


The Medtronic Symplicity™ blood pressure procedure is a minimally invasive, investigational procedure that may help reduce high blood pressure without the need for additional medication.


Nerves in the kidney arteries play an important role in blood pressure management but they can become overactive in some people. This procedure calms excessively active nerve signals in those arteries that can affect blood pressure. After the procedure, individuals may experience lower blood pressure without additional medications. Some individuals may be able to reduce their hypertension medications.


Take a short survey to see if this study may be right for you.

See if you qualify

Is the High Blood Pressure Clinical Study right for you?

We are looking for participants who meet the following criteria:

  • Age 18 or older.
  • Have been diagnosed with hypertension by their healthcare provider.
  • Have a baseline office systolic blood pressure ≥140 mmHg.
  • Are willing to perform occasional at-home blood pressure readings.
  • Are willing to undergo a medical procedure that may require a short hospital stay.
See if you qualify

How to participate in the study.

Step 2

Speak with our Study Support Specialists about your eligibility and get matched with a local clinical study site.

Step 1

Take the survey to see if you qualify to join the clinical study.

Step 3

Attend seven doctor visits over the course of 36 months. During one of these visits, you will receive the Medtronic Symplicity™ blood pressure procedure.

Find out if you qualify for the High Blood Pressure Clinical Study.

Take a short survey to see if you qualify to join the High Blood Pressure Clinical Study. If you qualify, one of our Study Support Specialists will reach out soon to confirm your eligibility.

QUIZ WILL GO HERE

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Frequently asked questions.

What is recovery like?

Most individuals return to normal activities within a week after the procedure. Your doctor will let you know when you can resume normal activities.

Will I still need to take blood pressure medication after the procedure?

You should continue taking prescribed medications as directed by your doctor. Your doctor will let you know if and when you can stop taking your blood pressure medications.


Some people will need to continue taking prescribed hypertension medications, while others may be able to stop taking medications. Your doctor will work with you to find the right solution based on your particular needs.

Will everyone receive the investigational procedure?

Yes, all patients who meet the study criteria will receive the Medtronic Symplicity™ blood pressure procedure.

What are the most common side effects?

Pain and bruising at the incision site are the most common side effects of the procedure.

  1. World Health Organization. Hypertension fact sheet. 13 September 2019. https://www.who.int/news-room/fact-sheets/detail/hypertension
  2. Whelton P, Carey R, Aronow W, et. al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Originally published 13 Nov 2017 https://doi.org/10.1161/HYP.0000000000000065. Hypertension 2018;71:e13–e115
  3. Mayo Clinic. High blood pressure dangers: Hypertension’s effects on your body. https://www.mayoclinic.org/diseases-conditions/highblood-pressure/in-depth/high-blood-pressure/art-20045868
  4. AmericanHeartAssociation. https://newsroom.heart.org/news/high-blood-pressure-redefined-for-first-time-in-14-years-130-is-the-new-high

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